Constant Sirima unlocks the genetic diversity of parasites in non-human primates in Cameroon and Gabon

Constant Sirima's thesis, conducted at the Institute for Research and Development, reveals the presence of DNA from Mansonella sp. in the feces of non-human primates, a first that could transform the diagnosis of parasitic infections. This research, validated in 2021, highlights the importance of co-infections in the health of gorillas and chimpanzees, with implications for public health in Africa.

The epidemiology of parasitic infections in non-human primates (NHP) is a growing concern, particularly in Africa. NHPs, such as gorillas and chimpanzees, share their habitat with humans, increasing the risk of zoonotic transmission. Constant Sirima's research, in collaboration with IRD and INSERM, explores the genetic diversity of geohelminths and filariae, shedding light on complex interactions between parasites.

This research has allowed for the first-time detection of DNA from Mansonella sp. in the feces of non-human primates. The co-infections observed in gorillas with other parasites such as Oesophagostomum sp. and Necator sp. illustrate a dynamic parasitic ecosystem, where multiple pathogens interact, making the treatment of infections more complex and highlighting the importance of an integrated approach.

The results of this study open significant perspectives for public health and zoonoses research. Decision-makers must consider the impact of co-infections on the health of populations and invest in innovative solutions for the diagnosis and treatment of parasitic infections, in order to reduce treatment costs and improve community health.

« « The detection of DNA from Mansonella sp. in the feces of non-human primates is a breakthrough that could change our approach to diagnosing parasitic infections, » says Constant Sirima. »

« « This research highlights the importance of accessing knowledge about zoonoses, essential for informing the decisions of public health actors, » emphasizes the Lektaris team. »