Institut Pasteur's Manon Curaudeau Identifies the Squirrel Funisciurus Anerythrus as a Monkeypox Reservoir in Africa

Manon Curaudeau, a researcher at the Institut Pasteur, has identified the squirrel Funisciurus anerythrus as a probable reservoir of the monkeypox virus in Africa, a major advance for epidemic prevention. This finding, validated in 2025, underscores the importance of monitoring animal populations to anticipate health risks.

Research into the monkeypox virus (MPXV) has been advanced by Manon Curaudeau at the Institut Pasteur. Although first discovered in macaques in 1958, this virus poses public health challenges, particularly in West and Central Africa. Identifying animal reservoirs is essential to preventing future epidemics and understanding the virus's evolution.

Curaudeau used a multidisciplinary approach, combining ecological modeling and phylogeography, to establish that the squirrel F. anerythrus could be the primary reservoir of MPXV. Genetic analyses revealed geographic structuring within this species, suggesting that biogeographic barriers influence the virus's spread, further reinforcing the importance of surveillance.

The findings of this research carry strategic implications for decision-makers. They underscore the need for increased surveillance of animal populations to prevent future monkeypox outbreaks. Investors should also consider the growth potential of the public health market in West Africa by supporting research into animal reservoirs.

« "The squirrel Funisciurus anerythrus could play a key role in the epidemiological dynamics of monkeypox, which calls for particular attention to the surveillance of animal populations." »

« "This research highlights the importance of access to scientific knowledge to inform the decisions of public health stakeholders and investors." »